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[329] [330] In February 2022, he said that he has "been about 80% plant-based for the past five years of my life", [331] and in 2025 he said that eats "mostly plants." [332] He also says that while he occasionally still consumes smaller amounts of animal products, following a mostly plant-based diet is better for his "overall-health", and that James Cameron helped him to understand that it is better for the environment

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Harischandra DS, Ghaisas S, Zenitsky G et al (2019) Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

The 18% discontinuation rate at the highest dose means roughly 1 in 5 people cannot tolerate retatrutide at maximum dose